Stocks › PRAX
Praxis Precision Medicines, Inc.
PRAX·Nasdaq·
United States·USD
United States·USD$280.14
-3.42 (-1.21%)
Close · Oct 6, 2026 · Close Prices from Tiingo.com
PRAX
Praxis Precision Medicines, Inc. · Nasdaq
Nasdaq 100S&P 500
Filings
Default90D1Y5YALL
PRAXS&P 500 (rebased)
Congress BuyCongress SellInsider BuyInsider SellForm 1448-K ResultsLobbying
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Daily closes, adjusted for splits and dividends · Close Prices from Tiingo.comHover a marker, every one is a filing · move across the line for the crosshair
Congressional Trades
Recent trades of PRAX by members of U.S. Congress · 1 on record · 1 in the last 12 months
| Politician | Stock | Type | Filed | Traded | |
|---|---|---|---|---|---|
 Gilbert Ray Cisneros, Jr.House · D · CA |
PRAXPraxis Precision Medicines, Inc. · Stock |
Purchase $1,001 - $15,000 |
Sep 4, 2026 | Jul 30, 2026 | Filing ↗ |
Whale Activity
Position changes in PRAX reported for 2026-06-30 by 11 tracked institutional filers
- Increased3
- New2
- Held0
- Decreased2
- Closed0
- No prior filing4
| Filer | Shares | Value | Change |
|---|---|---|---|
| BlackRock, Inc. | 2.3M | $767.5M | decreased |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1.3M | $447.0M | increased |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.2M | $413.6M | increased |
| Affinity Asset Advisors, LLC | 185.0K | $61.9M | — |
| 72 Investment Holdings, LLC | 65.9K | $22.1M | — |
| TWO SIGMA INVESTMENTS, LP | 18.8K | $6.3M | increased |
| Atika Capital Management LLC | 12.9K | $4.3M | — |
| Seven Fleet Capital Management LP | 7,540 | $2.5M | — |
| CITADEL ADVISORS LLC | 7,331 | $2.5M | new |
| D. E. Shaw & Co., Inc. | 5,140 | $1.7M | new |
| MILLENNIUM MANAGEMENT LLC | 995 | $333K | decreased |
KeyVex tracks a curated set of large 13F filers plus the largest positions in recent filings, so this is a sample of institutional activity, not the whole market.
Insider Trading
Net shares bought (+) or sold (−) on the open market by PRAX insiders, by quarter · Form 4
Recent Insider Transactions
197 transactions on record · newest first
| Insider | Type | Shares | Price | Value | Date | |
|---|---|---|---|---|---|---|
| DeSimone JillDirector | Sale | −837 | $315.71 | $264K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −1,279 | $314.90 | $403K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −504 | $313.66 | $158K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −1,004 | $312.83 | $314K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −2,854 | $311.91 | $890K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −1,750 | $310.89 | $544K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −999 | $309.38 | $309K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −1,240 | $308.24 | $382K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −683 | $306.77 | $210K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −320 | $305.31 | $98K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −120 | $303.13 | $36K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Sale | −10 | $301.44 | $3K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Option exercise | +3,034 | $147.30 | $447K | Jun 24, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Option exercise | +8,566 | $44.25 | $379K | Jun 24, 2026 | Form 4 ↗ |
| Arbuckle Stuart ADirector | Grant / award | +1,371 | $0.00 | $0 | Jun 10, 2026 | Form 4 ↗ |
| Chodakewitz JeffreyDirector | Grant / award | +1,371 | $0.00 | $0 | Jun 10, 2026 | Form 4 ↗ |
| YOUNG WILLIAM DDirector | Grant / award | +1,371 | $0.00 | $0 | Jun 10, 2026 | Form 4 ↗ |
| DeSimone JillDirector | Grant / award | +1,371 | $0.00 | $0 | Jun 10, 2026 | Form 4 ↗ |
| Cudkowicz Merit EsterDirector | Grant / award | +1,371 | $0.00 | $0 | Jun 10, 2026 | Form 4 ↗ |
| MITCHELL DEAN JDirector | Grant / award | +1,371 | $0.00 | $0 | Jun 10, 2026 | Form 4 ↗ |
Fund Holders
Mutual funds and ETFs holding PRAX · SEC Form N-PORT
| Fund | Shares | Value | % of fund | As of |
|---|---|---|---|---|
| VANGUARD TOTAL STOCK MARKET INDEX FUND VANGUARD INDEX FUNDS | 885.4K | $296.4M | 0.01% | Jun 30, 2026 |
| iShares Russell 2000 ETF iShares Trust | 653.1K | $218.7M | 0.26% | Jun 30, 2026 |
| VANGUARD SMALL-CAP INDEX FUND VANGUARD INDEX FUNDS | 639.6K | $214.1M | 0.11% | Jun 30, 2026 |
| State Street(R) SPDR(R) S&P(R) Biotech ETF SPDR SERIES TRUST | 413.7K | $138.5M | 1.29% | Jun 30, 2026 |
| VANGUARD SMALL-CAP VALUE INDEX FUND VANGUARD INDEX FUNDS | 405.0K | $135.6M | 0.20% | Jun 30, 2026 |
| Select Biotechnology Portfolio Fidelity Select Portfolios | 371.4K | $130.0M | 2.47% | May 31, 2026 |
| Janus Henderson Global Life Sciences Fund Janus Investment Fund | 379.4K | $127.0M | 2.19% | Jun 30, 2026 |
| Janus Henderson Enterprise Fund Janus Investment Fund | 358.1K | $119.9M | 0.54% | Jun 30, 2026 |
| VANGUARD EXTENDED MARKET INDEX FUND VANGUARD INDEX FUNDS | 300.9K | $100.7M | 0.10% | Jun 30, 2026 |
| Fidelity Small Cap Index Fund Fidelity Salem Street Trust | 274.8K | $84.6M | 0.25% | Jul 31, 2026 |
Mutual funds and ETFs whose N-PORT filings list PRAX's shares (CUSIP 74006W207), each fund at its latest report since Mar 7, 2026, largest positions first. Bonds, options and short positions are left out.
Activist & Passive Stakes
Schedule 13D / 13G beneficial-ownership filings
- Allan Gray Australia Pty LtdSCHEDULE 13G/A · passive (13G) · 3,108 shares0.0%
Aug 14, 2026 · ↗ - ORBIS INVESTMENT MANAGEMENT LTDSCHEDULE 13G/A · passive (13G) · 1.5M shares5.5%
Aug 14, 2026 · ↗ - Felix J. BakerSCHEDULE 13G · passive (13G) · 1.8M shares6.3%
May 15, 2026 · ↗ - Julian C. BakerSCHEDULE 13G · passive (13G) · 1.8M shares6.3%
May 15, 2026 · ↗ - Baker Bros. Advisors (GP) LLCSCHEDULE 13G · passive (13G) · 1.8M shares6.3%
May 15, 2026 · ↗ - Baker Bros. Advisors LPSCHEDULE 13G · passive (13G) · 1.8M shares6.3%
May 15, 2026 · ↗ - Allan Gray Australia Pty LtdSCHEDULE 13G/A · passive (13G) · 4,067 shares0.0%
May 15, 2026 · ↗ - ORBIS INVESTMENT MANAGEMENT LTDSCHEDULE 13G/A · passive (13G) · 2.5M shares8.9%
May 15, 2026 · ↗ - Steven A. CohenSCHEDULE 13G/A · passive (13G) · 65.9K shares0.2%
May 15, 2026 · ↗ - 72 Investment Holdings, LLCSCHEDULE 13G/A · passive (13G) · 65.9K shares0.2%
May 15, 2026 · ↗
Corporate Lobbying
Estimated quarterly lobbying spending reported under the LDA, filings naming praxis precision medicines as client
- BALLARD PARTNERSPRAXIS PRECISION MEDICINES, INC. · 2026 Q3 · HCR—
Filing ↗ - THE KPM GROUP DC LLCPRAXIS PRECISION MEDICINES · 2026 Q2 · PHA$40K
Filing ↗ - THE KPM GROUP DC LLCPRAXIS PRECISION MEDICINES · 2026 Q2 · PHA$40K
Filing ↗ - THE KPM GROUP DC LLCPRAXIS PRECISION MEDICINES · 2026 Q1 · PHA$40K
Filing ↗ - THE KPM GROUP DC LLCPRAXIS PRECISION MEDICINES · 2025 Q4 · PHA$40K
Filing ↗
Government Contracts
Federal awards to Praxis Precision Medicines, Inc. · USAspending
No federal contract awards found for Praxis Precision Medicines, Inc..
U.S. Patents
Recent USPTO applications naming Praxis Precision Medicines, Inc.
No USPTO patent applications found for Praxis Precision Medicines, Inc..
Annual Financials
From PRAX's 10-K filings · XBRL
No annual XBRL figures on record for PRAX. KeyVex's fundamentals cover about 130 large companies so far.
Stock Splits
Every split and reverse split in the price history
- 1-for-15Reverse splitNov 29, 2023
Split dates and ratios from the price history · Close Prices from Tiingo.com
Material Events (8-K)
Corporate events filed with the SEC
- 8-K · Items 2.02, 7.01, 9.01Results of operations · Reg FD disclosureAug 6, 2026
EDGAR ↗ - 8-K · Items 8.01Other eventsJul 7, 2026
EDGAR ↗ - 8-K · Items 4.01, 9.01Change in auditorJul 2, 2026
EDGAR ↗ - 8-K · Items 8.01Other eventsJun 29, 2026
EDGAR ↗ - 8-K · Items 8.01Other eventsJun 22, 2026
EDGAR ↗ - 8-K · Items 5.07Shareholder voteJun 12, 2026
EDGAR ↗ - 8-K · Items 8.01Other eventsJun 1, 2026
EDGAR ↗ - 8-K · Items 2.02, 7.01, 9.01Results of operations · Reg FD disclosureMay 7, 2026
EDGAR ↗
About Praxis Precision Medicines, Inc.
From SEC EDGAR company records
Industry (SIC 2834)Pharmaceutical Preparations
SectorHealthcare
HeadquartersBOSTON, MA
IncorporatedDE
SEC CIK0001689548 ↗