Stocks › OPK

OPKO HEALTH, INC.

OPK·Nasdaq·United States United States·USD
$1.46
-0.11 (-7.01%)
Close · Oct 6, 2026 · Close Prices from Tiingo.com
OPK
OPKO HEALTH, INC. · Nasdaq
Nasdaq 100S&P 500
Filings
Default90D1Y5YALL
OPKS&P 500 (rebased)
Congress BuyCongress SellInsider BuyInsider SellForm 1448-K ResultsLobbying
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Daily closes, adjusted for splits and dividends · Close Prices from Tiingo.comHover a marker, every one is a filing · move across the line for the crosshair

Congressional Trades

Recent trades of OPK by members of U.S. Congress · 3 on record
All congressional trades →
PoliticianStockTypeFiledTraded
Carlos CurbeloCarlos CurbeloHouse · R · FL OPKOPKO HEALTH, INC. · Stock Purchase
$1,001 - $15,000
Oct 3, 2017 Sep 26, 2017 Filing ↗
Carlos Mr CurbeloCarlos Mr CurbeloHouse · R · FL OPKOPKO HEALTH, INC. · Stock Purchase
$1,001 - $15,000
Mar 2, 2017 Mar 2, 2017 Filing ↗
Carlos Mr CurbeloCarlos Mr CurbeloHouse · R · FL OPKOPKO HEALTH, INC. · Stock Purchase
$1,001 - $15,000
Feb 7, 2017 Feb 7, 2017 Filing ↗

Whale Activity

Position changes in OPK reported for 2026-06-30 by 9 tracked institutional filers
Increased: 5New: 1Decreased: 1Closed: 1No prior filing: 1
  • Increased5
  • New1
  • Held0
  • Decreased1
  • Closed1
  • No prior filing1
FilerSharesValueChange
BlackRock, Inc.37.0M$55.5Mincreased
VANGUARD CAPITAL MANAGEMENT LLC15.0M$22.5Mincreased
VANGUARD PORTFOLIO MANAGEMENT LLC14.9M$22.4Mincreased
PenderFund Capital Management Ltd.8.5M$12.8M—
CITADEL ADVISORS LLC1.4M$2.1Mdecreased
TWO SIGMA INVESTMENTS, LP175.8K$264Kincreased
Point72 Asset Management, L.P.145.2K$218Kincreased
MILLENNIUM MANAGEMENT LLC72.3K$108Knew
Renaissance Technologies0$0closed

KeyVex tracks a curated set of large 13F filers plus the largest positions in recent filings, so this is a sample of institutional activity, not the whole market.

Insider Trading

Net shares bought (+) or sold (−) on the open market by OPK insiders, by quarter · Form 4
-2.5M-1.3M01.3M2.5M2025 Q1: 1.1M2025 Q12025 Q2: 350.0K2025 Q22025 Q3: 675.0K2025 Q32025 Q4: 2.4M2025 Q42026 Q1: 10.0K2026 Q12026 Q2: 02026 Q22026 Q3: 02026 Q32026 Q4: 02026 Q4

Recent Insider Transactions

10,001 transactions on record · newest first
All insider activity →
InsiderTypeSharesPriceValueDate
PAGANELLI JOHN ADirector Purchase +10.0K $1.14 $11K Mar 20, 2026 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +192.9K $1.34 $258K Nov 21, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +191.5K $1.33 $255K Nov 21, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +89.4K $1.33 $119K Nov 21, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +3,894 $1.32 $5K Nov 21, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +102.4K $1.30 $133K Nov 21, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +13.7K $1.35 $18K Nov 20, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +1,757 $1.35 $2K Nov 20, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +24.6K $1.34 $33K Nov 20, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +161.8K $1.34 $217K Nov 20, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +211.9K $1.33 $282K Nov 20, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +47.1K $1.33 $63K Nov 20, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +119.1K $1.32 $157K Nov 20, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +155.5K $1.32 $205K Nov 19, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +198.9K $1.32 $263K Nov 19, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +66.5K $1.31 $87K Nov 19, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +13.0K $1.31 $17K Nov 19, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +30.1K $1.30 $39K Nov 19, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +21.2K $1.30 $28K Nov 19, 2025 Form 4 ↗
Frost Gamma Investments Trust10% owner Purchase +300 $1.29 $387 Nov 19, 2025 Form 4 ↗

Fund Holders

Mutual funds and ETFs holding OPK · SEC Form N-PORT
FundSharesValue% of fundAs of
iShares Russell 2000 ETF
iShares Trust
10.5M$15.7M0.02%Jun 30, 2026
VANGUARD TOTAL STOCK MARKET INDEX FUND
VANGUARD INDEX FUNDS
9.8M$14.6M0.00%Jun 30, 2026
VANGUARD SMALL-CAP INDEX FUND
VANGUARD INDEX FUNDS
6.9M$10.4M0.01%Jun 30, 2026
VANGUARD EXTENDED MARKET INDEX FUND
VANGUARD INDEX FUNDS
4.9M$7.4M0.01%Jun 30, 2026
Fidelity Small Cap Index Fund
Fidelity Salem Street Trust
4.4M$5.7M0.02%Jul 31, 2026
iShares Russell 2000 Value ETF
iShares Trust
3.8M$5.7M0.04%Jun 30, 2026
iShares Biotechnology ETF
iShares Trust
2.7M$4.0M0.04%Jun 30, 2026
Fidelity Extended Market Index Fund
Fidelity Concord Street Trust
2.3M$3.3M0.01%May 31, 2026
VANGUARD SMALL-CAP VALUE INDEX FUND
VANGUARD INDEX FUNDS
2.2M$3.3M0.00%Jun 30, 2026
VANGUARD RUSSELL 2000 INDEX FUND
VANGUARD SCOTTSDALE FUNDS
2.1M$3.1M0.02%May 31, 2026

Mutual funds and ETFs whose N-PORT filings list OPK's shares (CUSIP 68375N103), each fund at its latest report since Mar 7, 2026, largest positions first. Bonds, options and short positions are left out.

Activist & Passive Stakes

Schedule 13D / 13G beneficial-ownership filings
  • Frost Nevada Investments TrustSCHEDULE 13D/A · activist (13D) · 30.1M shares4.0%
    Jul 1, 2026 · ↗
  • Frost Gamma Investments TrustSCHEDULE 13D/A · activist (13D) · 216.7M shares29.0%
    Jul 1, 2026 · ↗
  • FROST PHILLIP MD ET ALSCHEDULE 13D/A · activist (13D) · 255.4M shares34.1%
    Jul 1, 2026 · ↗

Corporate Lobbying

Estimated quarterly lobbying spending reported under the LDA, filings naming opko health as client
$0$25K$50K$75K$100K2026 Q1: $23K2026 Q2: $45K2026
  • GOTHAM GOVERNMENT RELATIONSOPKO HEALTH, INC. · 2026 Q2 · HCR, MED, PHA$45K
    Filing ↗
  • GOTHAM GOVERNMENT RELATIONSOPKO HEALTH, INC. · 2026 Q1 · HCR$23K
    Filing ↗
  • GOTHAM GOVERNMENT RELATIONSOPKO HEALTH, INC. · 2026 Q1 · HCR, PHA—
    Filing ↗
  • CYRUS M. JOLLIVETTE PUBLIC AFFAIRS LLCOPKO HEALTH, INC. · 2016 Q3 · HCR$25K
    Filing ↗
  • CYRUS M. JOLLIVETTE PUBLIC AFFAIRS LLCOPKO HEALTH, INC. · 2016 Q2$25K
    Filing ↗

Government Contracts

Federal awards to OPKO HEALTH, INC. · USAspending

No federal contract awards found for OPKO HEALTH, INC..

U.S. Patents

Recent USPTO applications naming OPKO HEALTH, INC.

No USPTO patent applications found for OPKO HEALTH, INC..

Annual Financials

From OPK's 10-K filings · XBRL

No annual XBRL figures on record for OPK. KeyVex's fundamentals cover about 130 large companies so far.

Stock Splits

Every split and reverse split in the price history

No stock splits in OPK's price history.

Material Events (8-K)

Corporate events filed with the SEC
  • 8-K · Items 8.01Other eventsOct 2, 2026
    EDGAR ↗
  • 8-K · Items 1.01, 2.03, 9.01Material agreement · Direct financial obligationAug 14, 2026
    EDGAR ↗
  • 8-K · Items 2.02, 9.01Results of operationsJul 27, 2026
    EDGAR ↗
  • 8-K · Items 5.07Shareholder voteJun 18, 2026
    EDGAR ↗

About OPKO HEALTH, INC.

From SEC EDGAR company records
Industry (SIC 2834)Pharmaceutical Preparations
SectorHealthcare
HeadquartersMIAMI, FL
IncorporatedDE
Former namesEXEGENICS INC, eXegenics Inc, CYTOCLONAL PHARMACEUTICS INC /DE